Industries · Immuno-oncology

Immuno-oncology

OMICS4 runs the multi-omics profiling behind tumour microenvironment studies: bulk and single-cell RNA-seq, targeted quantification and, through our partnership with MIPP, plasma protein panels built for immuno-oncology.

Overview

Tumor and immune compartments, sequenced

OMICS4 runs the laboratory work behind immuno-oncology studies. Tumor and immune compartments are extracted, sequenced and quality-controlled in our own laboratories, and returned as primary data your team can analyse directly or hand to GenXMap.

Platforms

Platforms that run an IO study

Extraction & Quality Control

RNA and DNA recovered from difficult tumour material.

  • FFPE blocks and slides
  • Fresh-frozen tissue, PBMC, whole blood
  • Integrity and purity documented on every sample
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NGS & Molecular Biology

Sequencing and targeted quantification on the same material.

  • Bulk RNA-seq across a cohort
  • Single-cell RNA-seq for tumour and immune compartments
  • Whole exome and targeted panels on tumour DNA
  • qPCR and dPCR for confirmation of candidate markers
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Proteomics

Plasma protein measurement alongside the sequencing layers.

  • Targeted immuno-oncology panels by proximity extension assay, with MIPP
  • LC-MS/MS for untargeted profiling
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Samples we accept

FFPE blocks and slides, fresh-frozen tumour tissue, core biopsies, PBMC, whole blood, plasma and dissociated cell suspensions. Input amounts, RIN thresholds and DNA quality criteria are published per sample type. Archival and low-input material is handled routinely: if your material sits below the published thresholds, say so in the quote request and we will tell you what is feasible before you ship.

What you receive

A QC report for every sample. Demultiplexed FASTQ with run-level QC metrics for the sequencing services. Result tables for PCR and protein work.

Where the bench stops

Alignment, quantification, integration, biomarker discovery and modelling are not part of a platform booking. They are run by GenXMap's R&D team, as the Immune Response Signature Package, a programme designed for your industry rather than a line on a quote. Ask for it in the quote request and both are scoped together.

Immune Response Signature Package at GenXMap

Have a project in this space?

Tell us the sample type, the number of samples and the timeline.

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